ESTD PERPUSTAKAAN UNTAD
ESTD PERPUSTAKAAN UNTAD
| JudulProfil Rasio Neutrofil Limfosit (RNL) Pada Pasien COVID-19 Di Rumah Sakit Anutapura Palu |
| Nama: RAHAYU PRATIWI |
| Tahun: 2021 |
| Abstrak Profil Rasio Neutrofil Limfosit (RNL) Pada Pasien COVID-19 Di Rumah Sakit Anutapura Palu *Rahayu Pratiwi *Nur Syamsi, *Program Studi S1 Kedokteran, Universitas Tadulako **Bagian Farmakologi Fakultas Kedokteran, Universitas Tadulako ABSTRAK Latar belakang: Corona Virus Disease (COVID-19) adalah jenis virus baru yang secara umum menyebabkan gangguan saluran pernafasan. Secara Global, WHO melaporkan kasus COVID-19 dari 223 Negara pada tanggal 18 Agustus 2021 sebanyak 207.784.507 orang terkonfirmasi positif, 4.370.424 orang telah meninggal dunia. Salah satu pemeriksaan penunjang untuk membantu klasifikasi keparahan penyakit dan peringatan dini perkembangan penyakit COVID?19 adalah pengukuran Rasio Neutrofil Limfosit (RNL) yang dapat digunakan untuk diagnosis dan menilai prognosis pasien. Penelitian ini bertujuan untuk mengetahui bagaimana profil rasio neutrofil limfosit (RNL) pada pasien COVID-19 di Rumah Sakit Anutapura Palu. Metode: Jenis penelitian ini adalah kuantitatif dengan pendekatan deskriptif. Sampel penelitian ini adalah pasien COVID-19 terkonfirmasi positif yang melakukan pemeriksaan RNL di Rumah Sakit Anutapura Palu sebanyak 75 pasien menggunakan teknik sampling non-probabilitas secara purposive sampling. Instrumen yang digunakan dalam penelitian ini yaitu lembar pengumpulan data untuk melihat data pasien COVID-19. Teknik analisis data menggunakan distribusi frekuensi dari nilai leukosit, neutrofil, dan limfosit. Hasil: Hasil penelitian didapatkan bahwa rata-rata usia pasien COVID-19 di RS Anutapura Palu adalah 48,12. Kadar leukosit dari 75 sampel adalah 6,67% pasien leukopenia, 78,6% pasien normal, dan 14,6% pasien leukositosis. Kadar neutrofil didapatkan 16% pasien neutropenia, 53,3% pasien normal, dan 30,6% pasien neutrofilia. Kadar limfosit didapatkan 29,3% pasien limfopenia, 57,3% pasien normal, dan 13,3% pasien limfositosis. Kadar rasio neutrofil limfosit (RNL) didapatkan 65,3% orang berisiko rendah (< 3> 3,13). Kesimpulan: Kadar leukosit, neutrofil, dan limfosit pada pasien COVID-19 terkonfirmasi positif di RS Anutapura Palu masih dalam batas normal , dan rasio neutrofil limfosit (RNL) beresiko rendah. Kata kunci: COVID-19, Leukosit, Neutrofil, Limfosit, RNL Profile of Neutrofil Limfosit Ratio (RNL) on COVID-19 Patient in Anutapura Hospital Palu *Rahayu Pratiwi *Nur Syamsi, *Program Studi S1 Kedokteran, Universitas Tadulako **Bagian Farmakologi Fakultas Kedokteran, Universitas Tadulako ABSTRACT Background: Corona Virus Disease (COVID-19) is a new type of virus that generally causes respiratory tract disorders. Globally, WHO reported cases of COVID-19 from 223 countries on August 18, 2021, there were 207,784,507 people confirmed positive, 4,370,424 people had died. One of the supporting tests to help classify disease severity and early warning of COVID-19 disease progression is the measurement of the Neutrophil Lymphocyte Ratio (RNL) which can be used for diagnosis and assessing patient prognosis. This research intends to determine the profile of the neutrophil lymphocyte ratio (RNL) in COVID-19 patients at Anutapura Hospital Palu. Methods: This is quantitative research with a descriptive approach. The sample of this research were 75 confirmed positive COVID-19 patient who underwent RNL examination at the Anutapura Hospital Palu using a non-probability sampling technique which were selected through purposive sampling. The instrument used in this research was a data collection sheet to view data on COVID-19 patients. The data analysis technique used the frequency distribution of the values of leukocytes, neutrophils, and lymphocytes. Results: The results show that the average age of COVID-19 patients at Anutapura Hospital Palu was 48.12. The leukocyte levels from 75 samples were 6.67% of leukopenia patients, 78.6% of normal patients, and 14.6% of leukocytosis patients. Neutrophil levels were found in 16% of neutropenic patients, 53.3% of normal patients, and 30.6% of neutrophilic patients. Lymphocyte levels were found in 29.3% of patients with lymphopenia, 57.3% of normal patients, and 13.3% of patients with lymphocytosis. The neutrophil lymphocyte ratio (RNL) was found in 65.3% of low-risk people (<3>3.13). Conclusion: The levels of leukocytes, neutrophils, and lymphocytes in COVID-19 patients confirmed positive at the Anutapura Hospital Palu were still within normal limits, and the neutrophil lymphocyte ratio (RNL) is at low risk. Keywords: COVID-19, Leukocytes, Neutrophils, Lymphocytes, RNL |