ESTD PERPUSTAKAAN UNTAD
ESTD PERPUSTAKAAN UNTAD
| JudulPengaruh Variasi Konsentrasi HPMC (Hydroxypropyl Methylcellulose) Terhadap Sediaan Emulgel Ekstrak Bawang Putih (Allium Sativum L.) Sebagai Antijerawat |
| Nama: YEYEN APRIANA |
| Tahun: 2020 |
| Abstrak Garlic (Allium sativum L.) contains allisin compounds which can inhibit and kill bacteria that cause acne. Garlic anti-acne preparations are formulated in the form of emulgel. This study aims to determine the effect of variations in the concentration of HPMC (Hydroxypropyl methylcellulose) and which concentrations have good physical quality in garlic extract emulgel preparations as anti-acne. In this study HPMC was varied into concentrations of 3% (Formula 1), 4% (Formula 2), and 5% (Formula 3). Each formula was tested for physical quality and physical stability which included organoleptic, homogeneity, pH, dispersal, and viscosity tests. The results showed that the three formulas had pH values ranging from 6.54 to 6.55, viscosity ranged from 10026.6-31146.6 cP, and the spreadability was between 4.5-5.6 cm. Increasing the concentration of HPMC affects the physical quality, namely decreasing the value of viscosity and increasing the value of emulgel dispersion. Emulgel preparations that meet the best physical quality are formula 1 with a concentration of 3% HPMC. Garlic (Allium sativum L.) contains allisin compounds which can inhibit and kill bacteria that cause acne. Garlic anti-acne preparations are formulated in the form of emulgel. This study aims to determine the effect of variations in the concentration of HPMC (Hydroxypropyl methylcellulose) and which concentrations have good physical quality in garlic extract emulgel preparations as anti-acne. In this study HPMC was varied into concentrations of 3% (Formula 1), 4% (Formula 2), and 5% (Formula 3). Each formula was tested for physical quality and physical stability which included organoleptic, homogeneity, pH, dispersal, and viscosity tests. The results showed that the three formulas had pH values ranging from 6.54 to 6.55, viscosity ranged from 10026.6-31146.6 cP, and the spreadability was between 4.5-5.6 cm. Increasing the concentration of HPMC affects the physical quality, namely decreasing the value of viscosity and increasing the value of emulgel dispersion. Emulgel preparations that meet the best physical quality are formula 1 with a concentration of 3% HPMC. |